A time window for rescuing dying retinal ganglion cells

A time window for rescuing dying retinal ganglion cells

Abstract Background Retinal ganglion cell (RGC) degeneration and death cause vision loss in patients with glaucoma. Regulated cell death, once initiated, is generally considered to be an irreversible process. Recently, we showed that, by timely removing the cell death stimulus, stressed neuronal PC1...

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Bibliographic Details
Main Authors: Wenting You, Kèvin Knoops, Iris Boesten, Tos T. J. M. Berendschot, Marc A. M. J. van Zandvoort, Birke J. Benedikter, Carroll A. B. Webers, Chris P. M. Reutelingsperger, Theo G. M. F. Gorgels
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Primary RGCs
Mitochondrial fragmentation
PS exposure
Cytochrome c release
Reversible cell death program
Online Access:https://doi.org/10.1186/s12964-023-01427-3

Internet

https://doi.org/10.1186/s12964-023-01427-3

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