Inheritable epigenetic response towards foreign DNA entry by mammalian host cells: a guardian of genomic stability

Inheritable epigenetic response towards foreign DNA entry by mammalian host cells: a guardian of genomic stability

Apart from its well-documented role in long-term promoter silencing, the genome-wide distribution patterns of ~ 28 million methylated or unmethylated CpG dinucleotides, e. g. in the human genome, is in search of genetic functions. We have set out to study changes in the cellular CpG methylation prof...

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Bibliographic Details
Main Authors: Walter Doerfler, Stefanie Weber, Anja Naumann
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Epigenetics
Subjects:
dna methylation
foreign dna
transgenomic cells
alterations of cpg methylation profiles
inheritable epigenetic response
genomic stability
Online Access:http://dx.doi.org/10.1080/15592294.2018.1549463

Internet

http://dx.doi.org/10.1080/15592294.2018.1549463

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