Cognition as a mediator for gait and balance impairments in GBA-related Parkinson’s disease

Cognition as a mediator for gait and balance impairments in GBA-related Parkinson’s disease

Abstract The extent to which the heterogeneity of gait and balance problems in PD may be explained by genetic variation is unknown. Variants in the glucocerebrosidase (GBA) gene are the strongest known genetic risk factor for PD and are associated with greater motor and cognitive severity. However,...

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Bibliographic Details
Main Authors: Rosie Morris, Douglas N. Martini, Katrina Ramsey, Valerie E. Kelly, Katrijn Smulders, Amie Hiller, Kathryn A. Chung, Shu-Ching Hu, Cyrus P. Zabetian, Kathleen L. Poston, Ignacio F. Mata, Karen L. Edwards, Jodi Lapidus, Brenna Cholerton, Thomas J. Montine, Joseph F. Quinn, Fay Horak
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-022-00344-5

Internet

https://doi.org/10.1038/s41531-022-00344-5

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