Cognition as a mediator for gait and balance impairments in GBA-related Parkinson’s disease
Abstract The extent to which the heterogeneity of gait and balance problems in PD may be explained by genetic variation is unknown. Variants in the glucocerebrosidase (GBA) gene are the strongest known genetic risk factor for PD and are associated with greater motor and cognitive severity. However,...
Main Authors: | Rosie Morris, Douglas N. Martini, Katrina Ramsey, Valerie E. Kelly, Katrijn Smulders, Amie Hiller, Kathryn A. Chung, Shu-Ching Hu, Cyrus P. Zabetian, Kathleen L. Poston, Ignacio F. Mata, Karen L. Edwards, Jodi Lapidus, Brenna Cholerton, Thomas J. Montine, Joseph F. Quinn, Fay Horak |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-06-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-022-00344-5 |
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