Improving adoptive T cell therapy: the particular role of T cell costimulation, cytokines and post-transfer vaccination

Adoptive cellular therapy (ACT) is a form of immunotherapy whereby antigen-specific T cells are isolated or engineered, expanded ex vivo and transferred back to patients. Clinical benefit after ACT has been obtained in treatment of infection, various hematological malignancies and some solid tumors,...

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Bibliographic Details
Main Authors: Anke Redeker, Ramon Arens
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00345/full