Semimethylation is a feature of diffuse large B-cell lymphoma, and subgroups with poor prognosis are characterized by global hypomethylation and short telomere length

Semimethylation is a feature of diffuse large B-cell lymphoma, and subgroups with poor prognosis are characterized by global hypomethylation and short telomere length

Abstract Background Large B-cell lymphoma (LBCL) is the most common lymphoma and is known to be a biologically heterogeneous disease regarding genetic, phenotypic, and clinical features. Although the prognosis is good, one-third has a primary refractory or relapsing disease which underscores the imp...

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Bibliographic Details
Main Authors: Olivia Carlund, Elina Thörn, Pia Osterman, Maja Fors, Andy Dernstedt, Mattias N. E. Forsell, Martin Erlanson, Mattias Landfors, Sofie Degerman, Magnus Hultdin
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Clinical Epigenetics
Subjects:
Diffuse large-B cell lymphoma
High-grade B-cell lymphoma
Primary CNS lymphomas
DNA methylation
Telomere length
Predictive markers
Online Access:https://doi.org/10.1186/s13148-024-01680-4

Internet

https://doi.org/10.1186/s13148-024-01680-4

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