Single-cell transcriptome profiling reveals immune and stromal cell heterogeneity in primary Sjögren’s syndrome

Single-cell transcriptome profiling reveals immune and stromal cell heterogeneity in primary Sjögren’s syndrome

Summary: Primary Sjögren’s syndrome (pSS) is a complex autoimmune disease characterized by lymphocytic infiltration and exocrine dysfunction, particularly affecting the salivary gland (SG). We employed single-cell RNA sequencing to investigate cellular heterogeneity in 11 patients with pSS and 5 non...

Full description

Bibliographic Details
Main Authors: Nan Xiang, Hao Xu, Zhou Zhou, Junyu Wang, Pengfei Cai, Li Wang, Zhen Tan, Yingbo Zhou, Tianping Zhang, Jiayuan Zhou, Ke Liu, Songwen Luo, Minghao Fang, Guosheng Wang, Zhuo Chen, Chuang Guo, Xiaomei Li
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Molecular biology
Cell biology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223020205

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223020205

Similar Items