Serum vascular endothelial growth factor affects tissue fluid accumulation and is associated with deteriorating tissue perfusion and oxygenation in severe sepsis: a prospective observational study

Abstract Background Positive fluid balance and tissue fluid accumulation are associated with adverse outcomes in sepsis. Vascular endothelial growth factor (VEGF) increases in sepsis, promotes vascular permeability, and may affect tissue fluid accumulation and oxygenation. We used near-infrared spec...

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Main Authors: Chin-Kuo Lin, Ying-Huang Tsai, Kuo-Chin Kao, Chieh-Mo Lin, Shao-Kui Zhou, Meng-Chin Ho, Shu-Yi Huang, Yu-Hung Fang, Che-Chia Chang, Wei-Chun Lee, Yueh-Lin Lee, Min-Chi Chen, Meng-Jer Hsieh, Yu-Ching Lin, Ming-Szu Hung, Wen-Chun Kuo, Bor-Shyh Lin
Format: Article
Language:English
Published: BMC 2023-04-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-023-01119-1