RIPK3 Promotes JEV Replication in Neurons via Downregulation of IFI44L

RIPK3 Promotes JEV Replication in Neurons via Downregulation of IFI44L

Japanese encephalitis virus (JEV), the leading cause of viral encephalitis in Asia, is neurovirulent and neuroinvasive. Neurons are the main target of JEV infection and propagation. Receptor interacting serine/threonine-protein kinase 3 (RIPK3) has been reported to contribute to neuroinflammation an...

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Bibliographic Details
Main Authors: Peiyu Bian, Chuantao Ye, Xuyang Zheng, Chuanyu Luo, Jiali Yang, Mengyuan Li, Yuan Wang, Jing Yang, Yun Zhou, Fanglin Zhang, Jianqi Lian, Ying Zhang, Zhansheng Jia, Yingfeng Lei
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
Japanese encephalitis virus (JEV)
receptor interacting serine/threonine-protein kinase 3 (RIPK3)
interferon-induced protein 44-like gene (IFI44L)
neurons
cellular innate immune response
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00368/full

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https://www.frontiersin.org/article/10.3389/fmicb.2020.00368/full

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