Influence of Cluster-Situated Regulator PteF in Filipin Biosynthetic Cluster on Avermectin Biosynthesis in <i>Streptomyces avermitilis</i>

Influence of Cluster-Situated Regulator PteF in Filipin Biosynthetic Cluster on Avermectin Biosynthesis in <i>Streptomyces avermitilis</i>

Crosstalk regulation is widespread in <i>Streptomyces</i> species. Elucidating the influence of a specific regulator on target biosynthetic gene clusters (BGCs) and cell metabolism is crucial for strain improvement through regulatory protein engineering. PteF and PteR are two regulators...

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Bibliographic Details
Main Authors: Guozhong Du, Xue Yang, Zhengxiong Wu, Minghui Pan, Zhuoxu Dong, Yanyan Zhang, Wensheng Xiang, Shanshan Li
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Biology
Subjects:
avermectin
filipin
regulator
<i>Streptomyces avermitilis</i>
transcriptome
Online Access:https://www.mdpi.com/2079-7737/13/5/344

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https://www.mdpi.com/2079-7737/13/5/344

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