Loss of ZC4H2 and RNF220 Inhibits Neural Stem Cell Proliferation and Promotes Neuronal Differentiation

Loss of ZC4H2 and RNF220 Inhibits Neural Stem Cell Proliferation and Promotes Neuronal Differentiation

The ubiquitin E3 ligase RNF220 and its co-factor ZC4H2 are required for multiple neural developmental processes through different targets, including spinal cord patterning and the development of the cerebellum and the locus coeruleus. Here, we explored the effects of loss of ZC4H2 and RNF220 on the...

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Bibliographic Details
Main Authors: Longlong Zhang, Maosen Ye, Liang Zhu, Jingmei Cha, Chaocui Li, Yong-Gang Yao, Bingyu Mao
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
ZC4H2
RNF220
neural stem cell
proliferation
differentiation
Cend1
Online Access:https://www.mdpi.com/2073-4409/9/7/1600

Internet

https://www.mdpi.com/2073-4409/9/7/1600

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