Kre28–Spc105 interaction is essential for Spc105 loading at the kinetochore

Kinetochore (KTs) are macromolecular protein assemblies that attach sister chromatids to spindle microtubules (MTs) and mediate accurate chromosome segregation during mitosis. The outer KT consists of the KMN network, a protein super-complex comprising Knl1 (yeast Spc105), Mis12 (yeast Mtw1), and Nd...

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Bibliographic Details
Main Authors: Babhrubahan Roy, Janice Sim, Simon J. Y. Han, Ajit P. Joglekar
Format: Article
Language:English
Published: The Royal Society 2022-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.210274