Targeting the DP2 receptor alleviates muscle atrophy and diet‐induced obesity in mice through oxidative myofiber transition

Abstract Background Mammalian skeletal muscles consist of two main fibre types: slow‐twitch (type I, oxidative) and fast‐twitch (type IIa, fast oxidative; type IIb/IIx, fast glycolytic). Muscle fibre composition switch is closely associated with chronic diseases such as muscle atrophy, obesity, type...

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Bibliographic Details
Main Authors: Huying Ning, Huiwen Ren, Yan Zhao, HaiFang Yin, Zhenji Gan, Yujun Shen, Ying Yu
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Online Access:https://doi.org/10.1002/jcsm.13136