Hypolipidemic effect of ethanol extract from Chimonanthus nitens Oliv. leaves in hyperlipidemia rats via activation of the leptin/JAK2/STAT3 pathway

Hypolipidemic effect of ethanol extract from Chimonanthus nitens Oliv. leaves in hyperlipidemia rats via activation of the leptin/JAK2/STAT3 pathway

Highlights 1. COE improves lipid levels and lipase activities in hyperlipidemic rats. 2. COE ameliorates antioxidant enzyme activities and liver function in hyperlipidemic rats. 3. COE exerts a hypolipidemic effect by activating the leptin/JAK2/STAT3 pathway.

Bibliographic Details
Main Authors: Jianping Pan, Xilin Ouyang, Qi Jin, Wei Wang, Jiali Xie, Baoming Yu, Zhijie Ling, Qizhen Wu, Baoping Zheng
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Molecular Medicine
Subjects:
Chimonanthus nitens Oliv. leaf
Hyperlipidemia
Leptin/JAK2/STAT3 pathway
Lipid metabolism
Oxidative stress
Online Access:https://doi.org/10.1186/s10020-022-00589-z

Internet

https://doi.org/10.1186/s10020-022-00589-z

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