Cr(VI)-Induced Autophagy Protects L-02 Hepatocytes from Apoptosis Through the ROS-AKT-mTOR Pathway

Cr(VI)-Induced Autophagy Protects L-02 Hepatocytes from Apoptosis Through the ROS-AKT-mTOR Pathway

Background/Aims: Hexavalent chromium [Cr(VI)] pollution has become a global concern for both ecosystems and human health. Our previous study revealed Cr(VI) could induce both apoptosis and autophagy in L-02 hepatocytes. Here, we sought to explore the underlying mechanism of Cr(VI)-induced autophagy...

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Bibliographic Details
Main Authors: Qi Liang, Yuanyuan Xiao, Kaihua Liu, Caigao Zhong, Ming Zeng, Fang Xiao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cr(VI)
Autophagy
L-02 hepatocytes
Apoptosis
ROS
AKT-mTOR
Online Access:https://www.karger.com/Article/FullText/495713

Internet

https://www.karger.com/Article/FullText/495713

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