Integration of risk variants from GWAS with SARS-CoV-2 RNA interactome prioritizes FUBP1 and RAB2A as risk genes for COVID-19

Integration of risk variants from GWAS with SARS-CoV-2 RNA interactome prioritizes FUBP1 and RAB2A as risk genes for COVID-19

Abstract The role of host genetic factors in COVID-19 outcomes remains unclear despite various genome-wide association studies (GWAS). We annotate all significant variants and those variants in high LD (R2 > 0.8) from the COVID-19 host genetics initiative (HGI) and identify risk genes by recogniz...

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Bibliographic Details
Main Authors: Weiwen Shi, Mengke Chen, Tingting Pan, Mengjie Chen, Yongjun Cheng, Yimei Hao, Sheng Chen, Yuanjia Tang
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-44705-3

Internet

https://doi.org/10.1038/s41598-023-44705-3

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