Glucocorticoid activates STAT3 and NF-κB synergistically with inflammatory cytokines to enhance the anti-inflammatory factor TSG6 expression in mesenchymal stem/stromal cells

Glucocorticoid activates STAT3 and NF-κB synergistically with inflammatory cytokines to enhance the anti-inflammatory factor TSG6 expression in mesenchymal stem/stromal cells

Abstract Glucocorticoid (GC) is essential for maintaining immune homeostasis. While GC is known to regulate the expression of genes related to inflammation in immune cells, the effects of GC, especially in the presence of inflammation, on non-immune cells remain largely unexplored. In particular, th...

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Bibliographic Details
Main Authors: Peiqing Huang, Rongrong Sun, Chenchang Xu, Zixuan Jiang, Muqiu Zuo, Yinghong Li, Rui Liu, Pixia Gong, Yuyi Han, Jiankai Fang, Peishan Li, Changshun Shao, Yufang Shi
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06430-1

Internet

https://doi.org/10.1038/s41419-024-06430-1

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