Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation
<p>Abstract</p> <p>Background</p> <p>A deficiency in <it>Perk </it>(EIF2AK3) causes multiple neonatal defects in humans known as the Wolcott Rallison syndrome. <it>Perk KO </it>mice exhibit the same array of defects including permanent neonatal d...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-09-01
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| Series: | BMC Cell Biology |
| Online Access: | http://www.biomedcentral.com/1471-2121/10/61 |