Identification of Galectin-3 as Potential Biomarkers for Renal Fibrosis by RNA-Sequencing and Clinicopathologic Findings of Kidney Biopsy

Identification of Galectin-3 as Potential Biomarkers for Renal Fibrosis by RNA-Sequencing and Clinicopathologic Findings of Kidney Biopsy

Background: Galectin-3 (Gal-3) is a multifunctional glycan-binding protein shown to be linked to chronic inflammation and fibrogenesis. Plasma Gal-3 is associated with proteinuria and renal dysfunction, but its role has never been confirmed with kidney biopsy results. In our study, we aimed to explo...

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Bibliographic Details
Main Authors: Shuo-Ming Ou, Ming-Tsun Tsai, Huan-Yuan Chen, Fu-An Li, Wei-Cheng Tseng, Kuo-Hua Lee, Fu-Pang Chang, Yao-Ping Lin, Ruey-Bing Yang, Der-Cherng Tarng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Medicine
Subjects:
galectin-3
chronic kidney disease
tubular atrophy
interstitial fibrosis
kidney biopsy
RNA-sequencing analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.748225/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.748225/full

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