TOX3 Promotes Ovarian Estrogen Synthesis: An RNA-Sequencing and Network Study

TOX3 Promotes Ovarian Estrogen Synthesis: An RNA-Sequencing and Network Study

BackgroundWomen who undergo chronic exposure to excessive estrogen are at a high risk of developing breast cancer. TOX3 has been reported to be highly expressed in breast tumors and is closely related to estrogen receptors. However, the effect of TOX3 on estrogen synthesis remains poorly understood....

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Bibliographic Details
Main Authors: Yuanyuan Man, Rusong Zhao, Xueying Gao, Yue Liu, Shigang Zhao, Gang Lu, Wai-Yee Chan, Peter C. K. Leung, Yuehong Bian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Endocrinology
Subjects:
TOX3/TNRC9
breast cancer
KGN
estrogen
RNA-Seq
GSEA
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.615846/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2020.615846/full

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