Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells

Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells

The aryl hydrocarbon receptor (AhR) plays a wide range of physiological roles in cellular processes such as proliferation, migration or control of immune responses. Several studies have also indicated that AhR might contribute to the regulation of energy balance or cellular metabolism. We observed t...

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Bibliographic Details
Main Authors: Martina Karasová, Jiřina Procházková, Zuzana Tylichová, Radek Fedr, Miroslav Ciganek, Miroslav Machala, Zdeněk Dvořák, Barbora Vyhlídalová, Iveta Zůvalová, Jiří Ehrmann, Jan Bouchal, Zdeněk Andrysík, Jan Vondráček
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cancers
Subjects:
colon cancer cells
AhR
metabolism
proliferation
fatty acid synthesis
Akt pathway
Online Access:https://www.mdpi.com/2072-6694/14/17/4245

Internet

https://www.mdpi.com/2072-6694/14/17/4245

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