Integrating binding and expression data to predict transcription factors combined function

Abstract Background Transcription factor binding to the regulatory region of a gene induces or represses its gene expression. Transcription factors share their binding sites with other factors, co-factors and/or DNA-binding proteins. These proteins form complexes which bind to the DNA as one-units....

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Bibliographic Details
Main Authors: Mahmoud Ahmed, Do Sik Min, Deok Ryong Kim
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-020-06977-1