The effect of postmenopausal osteoporosis on subchondral bone pathology in a rat model of knee osteoarthritis
Abstract This study aimed to investigate the additional effect of ovariectomy-induced osteoporosis (OP) on the pathology of knee osteoarthritis (OA) in a rat meniscectomized model, particularly focusing on subchondral bone changes and pain behaviour. Rats were divided into four groups, sham, OP, OA,...
Main Authors: | Hiroyuki Wada, Koji Aso, Masashi Izumi, Masahiko Ikeuchi |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-29802-7 |
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