Therapeutic efficacy of generic artemether–lumefantrine in the treatment of uncomplicated malaria in Ghana: assessing anti-malarial efficacy amidst pharmacogenetic variations

Therapeutic efficacy of generic artemether–lumefantrine in the treatment of uncomplicated malaria in Ghana: assessing anti-malarial efficacy amidst pharmacogenetic variations

Abstract Background Despite efforts made to reduce morbidity and mortality associated with malaria, especially in sub-Saharan Africa, malaria continues to be a public health concern that requires innovative efforts to reach the WHO-set zero malaria agenda. Among the innovations is the use of artemis...

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Bibliographic Details
Main Authors: Nicholas Ekow Thomford, Tracy Kellermann, Robert Peter Biney, Charné Dixon, Samuel Badu Nyarko, Richmond Owusu Ateko, Martins Ekor, George B. Kyei
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Malaria Journal
Subjects:
Pharmacogenomics
Pharmacokinetics
Generic anti-malarials
Artemether–lumefantrine
CYP2B6
CYP3A5
Online Access:https://doi.org/10.1186/s12936-024-04930-1

Internet

https://doi.org/10.1186/s12936-024-04930-1

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