BCL10GFP fusion protein as a substrate for analysis of determinants required for Mucosa-Associated Lymphoid Tissue 1 (MALT1)-mediated cleavage

<p>Abstract</p> <p>Background</p> <p>MALT1 belongs to a family of paracaspase and modulates NF-κB signaling pathways through its scaffolding function and proteolytic activity. MALT1 cleaves protein substrates after a positively charged Arginine residue. BCL10, a 233 ami...

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Bibliographic Details
Main Authors: Jou Shin-Yi, Chang Chien-Chih, Wu Chun-Hsien, Chen Mei-Ru, Tsai Ching-Hwa, Chuang Wen-Hui, Chen Yun-Hui, Cheng Ann-Lii, Doong Shin-Lian
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Journal of Biomedical Science
Subjects:
Online Access:http://www.jbiomedsci.com/content/19/1/85