Non-random spatial organization of telomeres varies during the cell cycle and requires LAP2 and BAF

Summary: Spatial genome organization within the nucleus influences major biological processes and is impacted by the configuration of linear chromosomes. Here, we applied 3D spatial statistics and modeling on high-resolution telomere and centromere 3D-structured illumination microscopy images in can...

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Bibliographic Details
Main Authors: Debora Keller, Sonia Stinus, David Umlauf, Edith Gourbeyre, Eric Biot, Nicolas Olivier, Pierre Mahou, Emmanuel Beaurepaire, Philippe Andrey, Laure Crabbe
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224005649