Intra-cerebroventricular Administration of Crocin Attenuates Sleep Deprivation-induced Hyperalgesia in Rats

Introduction: Sleep deprivation can cause hyperalgesia and interfere with analgesic treatments. The aim of the present study was to establish an obligatory sleep-abstinence model and also evaluate the effects of intracerebroventricular (ICV) injection of crocin on pain perception in Wistar rats. Met...

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Bibliographic Details
Main Authors: Faezeh Rezaei, Mohammad Reza Saebipour, Kazem Ghaemi, Mohammad Mehdi Hassanzadeh-Taheri, Mohsen Foadoddini, Mehran Hosseini
Format: Article
Language:English
Published: Iran University of Medical Sciences 2020-05-01
Series:Basic and Clinical Neuroscience
Subjects:
Online Access:http://bcn.iums.ac.ir/article-1-1210-en.html