Synthesis and Antitumor Activity of Erlotinib Derivatives Linked With 1,2,3-Triazole

Cervical cancer is one of the most important cause of cancer-related death and presents a major public health problem in many countries. To search for more novel antitumor agents against cervical cancer, 14 erlotinib-linked 1,2,3-triazole compounds were designed, synthesized, and evaluated for their...

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Bibliographic Details
Main Authors: Peng Deng, Ge Sun, Jie Zhao, Kaitai Yao, Miaomiao Yuan, Lizeng Peng, Longfei Mao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.793905/full