Amino acid sensor GCN2 promotes SARS-CoV-2 receptor ACE2 expression in response to amino acid deprivation

Amino acid deprivation increases ACE2 expression in the gut, potentially aggravating SARS-CoV-2 infection.

Bibliographic Details
Main Authors: Xiaoming Hu, Yuguo Niu, Peixiang Luo, Fei Xiao, Feixiang Yuan, Hanrui Yin, Shanghai Chen, Feifan Guo
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03609-0