Anti-Aspergillus activities of olorofim at sub-MIC levels during early-stage growth

Anti-Aspergillus activities of olorofim at sub-MIC levels during early-stage growth

ABSTRACTOlorofim, the first member of the novel class of antifungal drugs, the orotomides, shows promising anti-Aspergillus activity and is currently in phase III clinical development. Using high-throughput microscopy, we monitored olorofim’s antifungal potential at sub-minimum inhibitory concentrat...

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Bibliographic Details
Main Authors: Alexander Kühbacher, Mike Birch, Jason D. Oliver, Fabio Gsaller
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:Microbiology Spectrum
Subjects:
olorofim
voriconazole
Aspergillus
sub-MIC
high-throughput microscopy
antifungal susceptibility testing
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03304-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03304-23

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