Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations

Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations

The incidences of colorectal cancer (CRC) are continuously increasing in some areas of the world, including Malaysia. In this study, we aimed to characterize the landscape of somatic mutations using the whole-genome sequencing approach and identify druggable somatic mutations specific to Malaysian p...

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Bibliographic Details
Main Authors: Ryia Illani Mohd Yunos, Nurul-Syakima Ab Mutalib, Jia-shiun Khoo, Sazuita Saidin, Muhiddin Ishak, Saiful Effendi Syafruddin, Francis Yew Fu Tieng, Najwa Farhah Md Yusof, Mohd Ridhwan Abd Razak, Norshahidah Mahamad Nadzir, Nadiah Abu, Isa Md Rose, Ismail Sagap, Luqman Mazlan, Rahman Jamal
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
Malaysians colorectal cancer
whole genome sequencing
precision medicine
druggable alterations
RNF43
KDM4E
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.997747/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2022.997747/full

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