Overexpression of IL22 by adeno-associated virus effectively ameliorates dextran sulfate sodium-induced colitis in mice

Objective To investigate the effects of interleukin22 (IL22) in acute colitis induced by dextran sulfate sodium salt (DSS) in mice and its underlying mechanism. Methods Three IL22 knockout mice (IL22-/-) and 3 control mice (IL22+/+) of 8-week-old males were subjected from the same litter, and then h...

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Bibliographic Details
Main Authors: WU Tianyu, SONG Yalan, WU Jingfeng, ZHENG Zhiyuan
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2023-10-01
Series:陆军军医大学学报
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Online Access:http://aammt.tmmu.edu.cn/html/202307121.htm