Cilia-Mediated Hedgehog Signaling in Drosophila

Cilia mediate Hedgehog (Hh) signaling in vertebrates and Hh deregulation results in several clinical manifestations, such as obesity, cognitive disabilities, developmental malformations, and various cancers. Drosophila cells are nonciliated during development, which has led to the assumption that ci...

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Bibliographic Details
Main Authors: Anujaianthi Kuzhandaivel, Sebastian W. Schultz, Liza Alkhori, Mattias Alenius
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714002496