Evolution of satellite plasmids can prolong the maintenance of newly acquired accessory genes in bacteria

Newly acquired plasmids are frequently lost due to fitness costs. Here, Zhang et al. show that the evolution of satellite plasmids with gene deletions can reduce fitness costs by driving down the copy number of full plasmids and thus favor maintenance of the full plasmid and its novel accessory gene...

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Bibliographic Details
Main Authors: Xue Zhang, Daniel E. Deatherage, Hao Zheng, Stratton J. Georgoulis, Jeffrey E. Barrick
Format: Article
Language:English
Published: Nature Portfolio 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13709-x