TLR7 and IL-6 differentially regulate the effects of rotarod exercise on the transcriptomic profile and neurogenesis to influence anxiety and memory

Summary: Voluntary exercise is well known to benefit brain performance. In contrast, forced exercise induces inflammation-related stress responses and may cause psychiatric disorders. Here, we unexpectedly found that rotarod testing, a frequently applied assay for evaluating rodent motor coordinatio...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Yun-Fen Hung, Yi-Ping Hsueh
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Elsevier 2021-04-01
Cyfres:iScience
Pynciau:
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2589004221003527