TLR7 and IL-6 differentially regulate the effects of rotarod exercise on the transcriptomic profile and neurogenesis to influence anxiety and memory

Summary: Voluntary exercise is well known to benefit brain performance. In contrast, forced exercise induces inflammation-related stress responses and may cause psychiatric disorders. Here, we unexpectedly found that rotarod testing, a frequently applied assay for evaluating rodent motor coordinatio...

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Bibliografiske detaljer
Main Authors: Yun-Fen Hung, Yi-Ping Hsueh
Format: Article
Sprog:English
Udgivet: Elsevier 2021-04-01
Serier:iScience
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004221003527