Dkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair.

Dkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair.

The mouse hair coat comprises protective "primary" and thermo-regulatory "secondary" hairs. Primary hair formation is ectodysplasin (Eda) dependent, but it has been puzzling that Tabby (Eda(-/y)) mice still make secondary hair. We report that Dickkopf 4 (Dkk4), a Wnt antagonist,...

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Bibliographic Details
Main Authors: Chang-Yi Cui, Makoto Kunisada, Yulan Piao, Victoria Childress, Minoru S H Ko, David Schlessinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2850388?pdf=render

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http://europepmc.org/articles/PMC2850388?pdf=render

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