Automated quantification reveals hyperglycemia inhibits endothelial angiogenic function.

Diabetes Mellitus (DM) has reached epidemic levels globally. A contributing factor to the development of DM is high blood glucose (hyperglycemia). One complication associated with DM is a decreased angiogenesis. The Matrigel tube formation assay (TFA) is the most widely utilized in vitro assay desig...

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Bibliographic Details
Main Authors: Anthony R Prisco, John D Bukowy, Brian R Hoffmann, Jamie R Karcher, Eric C Exner, Andrew S Greene
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3981811?pdf=render