Mutations in SARS-CoV-2 variant nsp6 enhance type-I interferon antagonism

Mutations in SARS-CoV-2 variant nsp6 enhance type-I interferon antagonism

ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve after its emergence. Given its importance in viral infection and vaccine development, mutations in the viral Spike gene have been studied extensively; however, the impact of mutations outside the Spike gene are...

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Bibliographic Details
Main Authors: Cody J. Bills, Hongjie Xia, John Yun-Chung Chen, Jason Yeung, Birte K. Kalveram, David Walker, Xuping Xie, Pei-Yong Shi
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
SARS-CoV-2
variants
nsp6
interferon
cytokine storm
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2209208

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2023.2209208

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