Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent manner.

Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent manner.

Opiates are among the most prescribed drugs for pain management. However, morphine use or abuse results in significant gut bacterial translocation and predisposes patients to serious infections with gut origin. The mechanism underlying this defect is still unknown. In this report, we investigated th...

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Bibliographic Details
Main Authors: Jingjing Meng, Haidong Yu, Jing Ma, Jinghua Wang, Santanu Banerjee, Rick Charboneau, Roderick A Barke, Sabita Roy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23349783/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23349783/?tool=EBI

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