Regioselectivity in the Ring Opening of Epoxides for the Synthesis of Aminocyclitols from D-(-)-Quinic Acid

Efficient syntheses of four aminocyclitols are reported. Each synthesis is accomplished in eight steps starting from D-(-)-quinic acid. The key step involves a highly regioselective ring opening of epoxides by sodium azide.

Bibliographic Details
Main Authors: Shu-Yu Yang, Tzenge-Lien Shih
Format: Article
Language:English
Published: MDPI AG 2012-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/4/4498/