Characterization of a novel interaction between Bcl-2 members Diva and Harakiri.

Interactions within proteins of the Bcl-2 family are key in the regulation of apoptosis. The death-inducing members control apoptotic mechanisms partly by antagonizing the prosurvival proteins through heterodimer formation. Structural and biophysical studies on these complexes are providing importan...

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Bibliographic Details
Main Authors: Lorenzo Sborgi, Susana Barrera-Vilarmau, Patricia Obregón, Eva de Alba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3012698?pdf=render