Integrative CRISPR Activation and Small Molecule Inhibitor Screening for lncRNA Mediating BRAF Inhibitor Resistance in Melanoma

The incidence of melanoma, being one of the most commonly occurring cancers, has been rising since the past decade. Patients at advanced stages of the disease have very poor prognoses, as opposed to at the earlier stages. The conventional targeted therapy is well defined and effective for advanced-s...

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Bibliographic Details
Main Authors: Sama Shamloo, Andreas Kloetgen, Stavroula Petroulia, Kathryn Hockemeyer, Sonja Sievers, Aristotelis Tsirigos, Ioannis Aifantis, Jochen Imig
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/7/2054