Ten-Eleven Translocation 1 and 2 Enzymes Affect Human Skin Fibroblasts in an Age-Related Manner

Ten-Eleven Translocation 1 and 2 Enzymes Affect Human Skin Fibroblasts in an Age-Related Manner

Ten-eleven translocation (TET) enzymes catalyze the oxidation of 5-methylcytosine (5mC), first to 5-hydroxymethylcytosine (5hmC), then to 5-formylcytosine (5fC), and finally to 5-carboxycytosine (5caC). Evidence suggests that changes in TET expression may impact cell function and the phenotype of ag...

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Bibliographic Details
Main Authors: Paulina Kołodziej-Wojnar, Joanna Borkowska, Anna Domaszewska-Szostek, Olga Bujanowska, Bartłomiej Noszczyk, Natalia Krześniak, Marek Stańczyk, Monika Puzianowska-Kuznicka
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomedicines
Subjects:
human primary fibroblasts
ten-eleven translocation methylcytosine dioxygenase 1 (TET1)
ten-eleven translocation methylcytosine dioxygenase 2 (TET2)
intrinsic aging
proliferation
apoptosis
Online Access:https://www.mdpi.com/2227-9059/11/6/1659

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https://www.mdpi.com/2227-9059/11/6/1659

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