Analysis of Astroglial Secretomic Profile in the Mecp2-Deficient Male Mouse Model of Rett Syndrome

Analysis of Astroglial Secretomic Profile in the Mecp2-Deficient Male Mouse Model of Rett Syndrome

Mutations in the X-linked <i>MECP2</i> gene are responsible for Rett syndrome (RTT), a severe neurological disorder. MECP2 is a transcriptional modulator that finely regulates the expression of many genes, specifically in the central nervous system. Several studies have functionally link...

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Bibliographic Details
Main Authors: Yann Ehinger, Valerie Matagne, Valérie Cunin, Emilie Borloz, Michel Seve, Sandrine Bourgoin-Voillard, Ana Borges-Correia, Laurent Villard, Jean-Christophe Roux
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
astrocytes
iTRAQ quantitative proteomic approach
Mecp2
neuronal arborization
Rett syndrome
secretome
Online Access:https://www.mdpi.com/1422-0067/22/9/4316

Internet

https://www.mdpi.com/1422-0067/22/9/4316

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