Ionic Regulation of T-Cell Function and Anti-Tumour Immunity

Ionic Regulation of T-Cell Function and Anti-Tumour Immunity

The capacity of T cells to identify and kill cancer cells has become a central pillar of immune-based cancer therapies. However, T cells are characterized by a dysfunctional state in most tumours. A major obstacle for proper T-cell function is the metabolic constraints posed by the tumour microenvir...

Full description

Bibliographic Details
Main Authors: Pierpaolo Ginefra, Helen Carrasco Hope, Mattia Spagna, Alessandra Zecchillo, Nicola Vannini
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
T cell
ions
tumour microenvironment
immunomodulation
nutrient competition
Online Access:https://www.mdpi.com/1422-0067/22/24/13668

Internet

https://www.mdpi.com/1422-0067/22/24/13668

Similar Items