OXIDATIVE STRESS-DEPENDENT ALTERED IMMUNE RESPONSES AND CELL DEATH IN SUBSTANTIA NIGRA AFTER OZONE EXPOSURE IN RAT

OXIDATIVE STRESS-DEPENDENT ALTERED IMMUNE RESPONSES AND CELL DEATH IN SUBSTANTIA NIGRA AFTER OZONE EXPOSURE IN RAT

Parkinson’s disease has been associated with the selective loss of neurons in the substantia nigra pars compacta. Increasing evidence suggests that oxidative stress plays a major role. The resulting increase in reactive oxygen species triggers a sequence of events that leads to cell damage, activati...

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Bibliographic Details
Main Authors: Selva eRivas - Arancibia, Luis Fernando Hernandez - Zimbron, Ana Erika Rodriguez - Martinez, Perla eDeyanira-Maldonado, Gabino eBorgonio - Perez, Maria eSepulveda - Parada
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Inflammation
Oxidative Stress
Ozone
Substantia Nigra
neurodegeneration
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00065/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00065/full

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