E-cadherin Interacts With Posttranslationally-Modified AGO2 to Enhance miRISC Activity

E-cadherin Interacts With Posttranslationally-Modified AGO2 to Enhance miRISC Activity

MicroRNAs (miRNAs) are small non-coding RNAs which post-transcriptionally suppress target mRNAs expression and/or translation to modulate pathophyological processes. Expression and function of miRNAs are fine-tuned by a conserved biogenesis machinery involves two RNase-dependent processing steps of...

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Bibliographic Details
Main Authors: Jie-Ning Li, Hui-Lung Sun, Ming-Yang Wang, Pai-Sheng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
E-cadherin
AGO2
miRISC activity
protein stability
miRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.671244/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.671244/full

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