Stem Cell Niche Dynamics: From Homeostasis to Carcinogenesis

The stem cell microenvironment is involved in regulating the fate of the stem cell with respect to self-renewal, quiescence, and differentiation. Mathematical models are helpful in understanding how key pathways regulate the dynamics of stem cell maintenance and homeostasis. This tight regulation a...

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Bibliographic Details
Main Authors: Kevin S. Tieu, Ryan S. Tieu, Julian A. Martinez-Agosto, Mary E. Sehl
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2012/367567