Comparison of two assays to detect IgG antibodies to the receptor binding domain of SARS‑CoV‑2 as a surrogate marker for assessing neutralizing antibodies in COVID-19 patients

Comparison of two assays to detect IgG antibodies to the receptor binding domain of SARS‑CoV‑2 as a surrogate marker for assessing neutralizing antibodies in COVID-19 patients

Background: Neutralizing antibodies (NAbs) are important for protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection. In this study, two assays that are correlated with NAbs were compared: the haemagglutination test (HAT) and the surrogate virus neutralization tes...

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Bibliographic Details
Main Authors: Achala Kamaladasa, Banuri Gunasekara, Chandima Jeewandara, Deshni Jayathilaka, Ananda Wijewickrama, Dinuka Guruge, Ruwan Wijayamuni, T.K. Tan, Graham S. Ogg, Alain Townsend, Gathsaurie Neelika Malavige
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:International Journal of Infectious Diseases
Subjects:
COVID-19
Disease severity
Haemagglutination assay
Surrogate neutralization assay
Neutralizing antibodies
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971221005208

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http://www.sciencedirect.com/science/article/pii/S1201971221005208

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